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Building and remodelling Cullin–RING E3 ubiquitin ligases

Cullin–RING E3 ubiquitin ligases (CRLs) control a plethora of biological pathways through targeted ubiquitylation of signalling proteins. These modular assemblies use substrate receptor modules to recruit specific targets. Recent efforts have focused on understanding the mechanisms that control the...

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Bibliografske podrobnosti
Main Authors: Lydeard, John R, Schulman, Brenda A, Harper, J Wade
Format: Artigo
Jezik:Inglês
Izdano: European Molecular Biology Organization 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849489/
https://ncbi.nlm.nih.gov/pubmed/24232186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2013.173
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