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Structural regulation of cullin-RING ubiquitin ligase complexes

Cullin-RING ligases (CRLs) compose the largest class of E3 ubiquitin ligases. CRLs are modular, multisubunit enzymes, comprising interchangeable substrate receptors dedicated to particular Cullin-RING catalytic cores. Recent structural studies have revealed numerous ways in which CRL E3 ligase activ...

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Main Authors: Duda, David M., Scott, Daniel C., Calabrese, Matthew F., Zimmerman, Erik S., Zheng, Ning, Schulman, Brenda A.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151539/
https://ncbi.nlm.nih.gov/pubmed/21288713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2011.01.003
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