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Inhibitors of cullin-RING E3 ubiquitin ligase 4 with antitumor potential
Cullin-RING (really intersting new gene) E3 ubiquitin ligases (CRLs) are the largest E3 family and direct numerous protein substrates for proteasomal degradation, thereby impacting a myriad of physiological and pathological processes including cancer. To date, there are no reported small-molecule in...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7923628/ https://ncbi.nlm.nih.gov/pubmed/33602808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2007328118 |
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