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Crystal structure of the catalytic C‐lobe of the HECT‐type ubiquitin ligase E6AP
The HECT‐type ubiquitin ligase E6AP (UBE3A) is critically involved in several neurodevelopmental disorders and human papilloma virus‐induced cervical tumorigenesis; the structural mechanisms underlying the activity of this crucial ligase, however, are incompletely understood. Here, we report a cryst...
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| Publicado no: | Protein Sci |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7255509/ https://ncbi.nlm.nih.gov/pubmed/31994269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3832 |
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