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Physical and Functional Interaction of the HECT Ubiquitin-protein Ligases E6AP and HERC2

Deregulation of the ubiquitin-protein ligase E6AP contributes to the development of the Angelman syndrome and to cervical carcinogenesis suggesting that the activity of E6AP needs to be under tight control. However, how E6AP activity is regulated at the post-translational level under non-pathologic...

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Autores principales: Kühnle, Simone, Kogel, Ulrike, Glockzin, Sandra, Marquardt, Andreas, Ciechanover, Aaron, Matentzoglu, Konstantin, Scheffner, Martin
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103319/
https://ncbi.nlm.nih.gov/pubmed/21493713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.205211
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