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Role of ubiquitin and the HPV E6 oncoprotein in E6AP-mediated ubiquitination
Deregulation of the ubiquitin ligase E6 associated protein (E6AP) encoded by the UBE3A gene has been associated with three different clinical pictures. Hijacking of E6AP by the E6 oncoprotein of distinct human papillomaviruses (HPV) contributes to the development of cervical cancer, whereas loss of...
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| Опубликовано в: : | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4538620/ https://ncbi.nlm.nih.gov/pubmed/26216987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505923112 |
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