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Structure of the HHARI Catalytic Domain Shows Glimpses of a HECT E3 Ligase
The ubiquitin-signaling pathway utilizes E1 activating, E2 conjugating, and E3 ligase enzymes to sequentially transfer the small modifier protein ubiquitin to a substrate protein. During the last step of this cascade different types of E3 ligases either act as scaffolds to recruit an E2 enzyme and s...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3772753/ https://ncbi.nlm.nih.gov/pubmed/24058416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074047 |
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