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Structure–Activity Relationship for the Oxadiazole Class of Antibacterials

[Image: see text] A structure–activity relationship (SAR) for the oxadiazole class of antibacterials was evaluated by syntheses of 72 analogs and determination of the minimal-inhibitory concentrations (MICs) against the ESKAPE panel of bacteria. Selected compounds were further evaluated for in vitro...

詳細記述

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書誌詳細
出版年:ACS Med Chem Lett
主要な著者: Boudreau, Marc A., Ding, Derong, Meisel, Jayda E., Janardhanan, Jeshina, Spink, Edward, Peng, Zhihong, Qian, Yuanyuan, Yamaguchi, Takao, Testero, Sebastian A., O’Daniel, Peter I., Leemans, Erika, Lastochkin, Elena, Song, Wei, Schroeder, Valerie A., Wolter, William R., Suckow, Mark A., Mobashery, Shahriar, Chang, Mayland
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2019
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073871/
https://ncbi.nlm.nih.gov/pubmed/32184964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00379
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