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Characterization of lead compounds targeting the selenoprotein thioredoxin glutathione reductase for treatment of schistosomiasis

Schistosomiasis is a widespread human parasitic disease currently affecting over 200 million people. Chemotherapy for schistosomiasis relies exclusively on praziquantel. Although significant advances have been made in recent years to reduce the incidence and intensity of schistosome infections, thes...

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Vydáno v:ACS Infect Dis
Hlavní autoři: Lyu, Haining, Petukhov, Pavel A., Banta, Paul R., Jadhav, Ajit, Lea, Wendy A., Cheng, Qing, Arnér, Elias S. J., Simeonov, Anton, Thatcher, Gregory R. J., Angelucci, Francesco, Williams, David L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072008/
https://ncbi.nlm.nih.gov/pubmed/31939288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.9b00354
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