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Inhibition and crosslinking of the selenoprotein thioredoxin reductase-1 by p-benzoquinone
Quinones are common in nature, and often cytotoxic. Their proposed toxicity mechanisms involve redox cycling with radical generation, and/or reactions with nucleophiles, such as protein cysteine (Cys) residues, forming adducts via Michael addition reactions. The selenenyl anion of selenocysteine (Se...
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| Publicado no: | Redox Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6812298/ https://ncbi.nlm.nih.gov/pubmed/31590044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101335 |
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