Characterization of lead compounds targeting the selenoprotein thioredoxin glutathione reductase for treatment of schistosomiasis

Schistosomiasis is a widespread human parasitic disease currently affecting over 200 million people. Chemotherapy for schistosomiasis relies exclusively on praziquantel. Although significant advances have been made in recent years to reduce the incidence and intensity of schistosome infections, thes...

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Veröffentlicht in:ACS Infect Dis
Hauptverfasser: Lyu, Haining, Petukhov, Pavel A., Banta, Paul R., Jadhav, Ajit, Lea, Wendy A., Cheng, Qing, Arnér, Elias S. J., Simeonov, Anton, Thatcher, Gregory R. J., Angelucci, Francesco, Williams, David L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072008/
https://ncbi.nlm.nih.gov/pubmed/31939288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.9b00354
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