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Characterization of lead compounds targeting the selenoprotein thioredoxin glutathione reductase for treatment of schistosomiasis

Schistosomiasis is a widespread human parasitic disease currently affecting over 200 million people. Chemotherapy for schistosomiasis relies exclusively on praziquantel. Although significant advances have been made in recent years to reduce the incidence and intensity of schistosome infections, thes...

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Библиографические подробности
Опубликовано в: :ACS Infect Dis
Главные авторы: Lyu, Haining, Petukhov, Pavel A., Banta, Paul R., Jadhav, Ajit, Lea, Wendy A., Cheng, Qing, Arnér, Elias S. J., Simeonov, Anton, Thatcher, Gregory R. J., Angelucci, Francesco, Williams, David L.
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072008/
https://ncbi.nlm.nih.gov/pubmed/31939288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.9b00354
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