Druggability profile of stilbene-derived PPAR agonists: determination of physicochemical properties and PAMPA study

PPAR agonists represent a new therapeutic opportunity for the prevention and treatment of neurodegenerative disorders, but their pharmacological success depends on favourable pharmacokinetic properties and capability to cross the BBB. In this study, we assayed some PPAR agonists previously synthesiz...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Medchemcomm
Auteurs principaux: Linciano, Pasquale, De Filippis, Barbara, Ammazzalorso, Alessandra, Amoia, Pasquale, Cilurzo, Felisa, Fantacuzzi, Marialuigia, Giampietro, Letizia, Maccallini, Cristina, Petit, Charlotte, Amoroso, Rosa
Format: Artigo
Langue:Inglês
Publié: Royal Society of Chemistry 2019
Sujets:
Chemistry
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069374/
https://ncbi.nlm.nih.gov/pubmed/32206235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00286c
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires