Antiglioma Activity of Aryl and Amido-Aryl Acetamidine Derivatives Targeting iNOS: Synthesis and Biological Evaluation

[Image: see text] Nitric oxide is an important inflammation mediator with a recognized role in the development of different cancers. Gliomas are primary tumors of the central nervous system with poor prognosis, and the expression of the inducible nitric oxide synthase correlates with the degree of m...

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Publicado en:ACS Med Chem Lett
Autores principales: Maccallini, Cristina, Arias, Fabio, Gallorini, Marialucia, Amoia, Pasquale, Ammazzalorso, Alessandra, De Filippis, Barbara, Fantacuzzi, Marialuigia, Giampietro, Letizia, Cataldi, Amelia, Camacho, María Encarnación, Amoroso, Rosa
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2020
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7357225/
https://ncbi.nlm.nih.gov/pubmed/32676156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00285
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