Antiglioma Activity of Aryl and Amido-Aryl Acetamidine Derivatives Targeting iNOS: Synthesis and Biological Evaluation

[Image: see text] Nitric oxide is an important inflammation mediator with a recognized role in the development of different cancers. Gliomas are primary tumors of the central nervous system with poor prognosis, and the expression of the inducible nitric oxide synthase correlates with the degree of m...

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Publié dans:ACS Med Chem Lett
Auteurs principaux: Maccallini, Cristina, Arias, Fabio, Gallorini, Marialucia, Amoia, Pasquale, Ammazzalorso, Alessandra, De Filippis, Barbara, Fantacuzzi, Marialuigia, Giampietro, Letizia, Cataldi, Amelia, Camacho, María Encarnación, Amoroso, Rosa
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2020
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7357225/
https://ncbi.nlm.nih.gov/pubmed/32676156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00285
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