Selective YAP/TAZ Inhibition in Fibroblasts via Dopamine Receptor D1 Agonism Reverses Fibrosis

Tissue fibrosis is characterized by uncontrolled deposition and diminished clearance of fibrous connective tissue proteins, ultimately leading to organ scarring. Yes-associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ) have recently emerged as pivotal drivers of mes...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Haak, Andrew J., Kostallari, Enis, Sicard, Delphine, Ligresti, Giovanni, Choi, Kyoung Moo, Caporarello, Nunzia, Jones, Dakota L., Tan, Qi, Meridew, Jeffrey, Diaz Espinosa, Ana M., Aravamudhan, Aja, Maiers, Jessica L., Britt, Rodney D., Roden, Anja C., Pabelick, Christina M., Prakash, YS, Nouraie, Seyed Mehdi, Li, Xiaoyun, Zhang, Yingze, Kass, Daniel J., Lagares, David, Tager, Andrew M., Varelas, Xaralabos, Shah, Vijay H., Tschumperlin, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7066514/
https://ncbi.nlm.nih.gov/pubmed/31666402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aau6296
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados