TBK1 regulates YAP/TAZ and fibrogenic fibroblast activation

Idiopathic pulmonary fibrosis (IPF) results in scarring of the lungs by excessive extracellular matrix (ECM) production. Resident fibroblasts are the major cell type involved in ECM deposition. The biochemical pathways that facilitate pathological fibroblast activation leading to aberrant ECM deposi...

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Vydáno v:Am J Physiol Lung Cell Mol Physiol
Hlavní autoři: Aravamudhan, Aja, Haak, Andrew J., Choi, Kyoung Moo, Meridew, Jeffrey A., Caporarello, Nunzia, Jones, Dakota L., Tan, Qi, Ligresti, Giovanni, Tschumperlin, Daniel J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272740/
https://ncbi.nlm.nih.gov/pubmed/32159970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00324.2019
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