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TBK1 regulates YAP/TAZ and fibrogenic fibroblast activation

Idiopathic pulmonary fibrosis (IPF) results in scarring of the lungs by excessive extracellular matrix (ECM) production. Resident fibroblasts are the major cell type involved in ECM deposition. The biochemical pathways that facilitate pathological fibroblast activation leading to aberrant ECM deposi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Physiol Lung Cell Mol Physiol
Egile Nagusiak: Aravamudhan, Aja, Haak, Andrew J., Choi, Kyoung Moo, Meridew, Jeffrey A., Caporarello, Nunzia, Jones, Dakota L., Tan, Qi, Ligresti, Giovanni, Tschumperlin, Daniel J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272740/
https://ncbi.nlm.nih.gov/pubmed/32159970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00324.2019
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