TBK1 regulates YAP/TAZ and fibrogenic fibroblast activation

Idiopathic pulmonary fibrosis (IPF) results in scarring of the lungs by excessive extracellular matrix (ECM) production. Resident fibroblasts are the major cell type involved in ECM deposition. The biochemical pathways that facilitate pathological fibroblast activation leading to aberrant ECM deposi...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Aravamudhan, Aja, Haak, Andrew J., Choi, Kyoung Moo, Meridew, Jeffrey A., Caporarello, Nunzia, Jones, Dakota L., Tan, Qi, Ligresti, Giovanni, Tschumperlin, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272740/
https://ncbi.nlm.nih.gov/pubmed/32159970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00324.2019
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