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Intranasal administration of dantrolene increased brain concentration and duration
Dantrolene has been demonstrated to be neuroprotective for multiple neurodegenerative diseases. However, dantrolene’s limited penetration into the CNS hampers its effectiveness as a neuroprotective agent. Here, we studied whether the intranasal administration of dantrolene provided better penetratio...
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| Pubblicato in: | PLoS One |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7065741/ https://ncbi.nlm.nih.gov/pubmed/32160210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0229156 |
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