Intranasal administration of dantrolene increased brain concentration and duration

Dantrolene has been demonstrated to be neuroprotective for multiple neurodegenerative diseases. However, dantrolene’s limited penetration into the CNS hampers its effectiveness as a neuroprotective agent. Here, we studied whether the intranasal administration of dantrolene provided better penetratio...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Wang, Jintao, Shi, Yun, Yu, Shuchun, Wang, Yan, Meng, Qingcheng, Liang, Ge, Eckenhoff, Maryellen F., Wei, Huafeng
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2020
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065741/
https://ncbi.nlm.nih.gov/pubmed/32160210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0229156
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