Long Term Dantrolene Treatment Reduced Intraneuronal Amyloid in Aged Alzheimer Triple Transgenic Mice

Our previous study suggested that early dantrolene treatment reduced amyloid plaque burden and nearly abolished learning and memory loss in a triple transgenic Alzheimer's disease (3xTg-AD) mouse model. In this study, we investigated the long term treatment of dantrolene on amyloid and tau neur...

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Detalhes bibliográficos
Publicado no:Alzheimer Dis Assoc Disord
Main Authors: Wu, Zhen, Yang, Bin, Liu, Chunxia, Liang, Ge, Eckenhoff, Maryellen F., Liu, Weixia, Pickup, Stephen, Meng, Qingcheng, Tian, Yuke, Li, Shitong, Wei, Huafeng
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543576/
https://ncbi.nlm.nih.gov/pubmed/25650693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WAD.0000000000000075
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