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MAPK- and AKT-activated thyroid cancers are sensitive to group I PAK inhibition

The number of individuals who succumb to thyroid cancer has been increasing and those who are refractory to standard care have limited therapeutic options, highlighting the importance of developing new treatments for patients with aggressive forms of the disease. Mutational activation of MAPK signal...

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Bibliographische Detailangaben
Veröffentlicht in:Endocr Relat Cancer
Hauptverfasser: Knippler, Christina M., Saji, Motoyasu, Rajan, Neel, Porter, Kyle, La Perle, Krista M. D., Ringel, Matthew D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062234/
https://ncbi.nlm.nih.gov/pubmed/31146260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-19-0188
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