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THE PI3K-AKT-mTOR PATHWAY IN INITIATION AND PROGRESSION OF THYROID TUMORS

The Phosphoinositide 3 (OH) kinase (PI3K) signaling cascade is involved in regulating glucose uptake and metabolism, growth, motility, and other essential functions for cell survival. Unregulated activation of this pathway commonly occurs in cancer through a variety of mechanisms, including genetic...

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Hlavní autoři: Saji, Motoyasu, Ringel, Matthew D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849843/
https://ncbi.nlm.nih.gov/pubmed/19897009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2009.10.016
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