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Inhibition of the PI3K/AKT/mTOR Pathway in Solid Tumors
The phosphoinositide 3-kinase (PI3K) pathway plays an integral role in many cellular processes and is frequently altered in cancer, contributing to tumor growth and survival. Small molecule inhibitors have been developed that target the three major nodes of this pathway: PI3K, AKT, and mammalian tar...
Guardat en:
| Publicat a: | J Clin Oncol |
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| Autor principal: | |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Clinical Oncology
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6366304/ https://ncbi.nlm.nih.gov/pubmed/27621407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2014.59.0018 |
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