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Inhibition of the PI3K/AKT/mTOR Pathway in Solid Tumors
The phosphoinositide 3-kinase (PI3K) pathway plays an integral role in many cellular processes and is frequently altered in cancer, contributing to tumor growth and survival. Small molecule inhibitors have been developed that target the three major nodes of this pathway: PI3K, AKT, and mammalian tar...
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| Publicado no: | J Clin Oncol |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Clinical Oncology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6366304/ https://ncbi.nlm.nih.gov/pubmed/27621407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2014.59.0018 |
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