Apigenin in Combination with Akt Inhibition Significantly Enhances Thyrotropin-Stimulated Radioiodide Accumulation in Thyroid Cells

Background: Selectively increased radioiodine accumulation in thyroid cells by thyrotropin (TSH) allows targeted treatment of thyroid cancer. However, the extent of TSH-stimulated radioiodine accumulation in some thyroid tumors is not sufficient to confer therapeutic efficacy. Hence, it is of clinic...

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Autores principales: Lakshmanan, Aparna, Doseff, Andrea I., Ringel, Matthew D., Saji, Motoyasu, Rousset, Bernard, Zhang, Xiaoli, Jhiang, Sissy M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2014
Materias:
Thyroid Radiology and Nuclear Medicine
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026312/
https://ncbi.nlm.nih.gov/pubmed/24400871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2013.0614
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