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microRNA-339-5p modulates Na(+)/I(−) symporter-mediated radioiodide uptake

Na(+)/I(−) symporter (NIS)-mediated radioiodide uptake (RAIU) serves as the basis for targeted ablation of thyroid cancer remnants. However, many patients with thyroid cancer have reduced NIS expression/function and hence do not benefit from radioiodine therapy. microRNA (miR) has emerged as a promi...

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Bibliografske podrobnosti
izdano v:Endocr Relat Cancer
Main Authors: Lakshmanan, Aparna, Wojcicka, Anna, Kotlarek, Marta, Zhang, Xiaoli, Jazdzewski, Krystian, Jhiang, Sissy M
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298451/
https://ncbi.nlm.nih.gov/pubmed/25404690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-14-0439
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