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KT5823 Differentially Modulates Sodium Iodide Symporter Expression, Activity, and Glycosylation between Thyroid and Breast Cancer Cells

Na(+)/I(−) symporter (NIS)-mediated iodide uptake into thyroid follicular cells serves as the basis of radioiodine therapy for thyroid cancer. NIS protein is also expressed in the majority of breast tumors, raising potential for radionuclide therapy of breast cancer. KT5823, a staurosporine-related...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Beyer, Sasha, Lakshmanan, Aparna, Liu, Yu-Yu, Zhang, Xiaoli, Wapnir, Irene, Smolenski, Albert, Jhiang, Sissy
פורמט: Artigo
שפה:Inglês
יצא לאור: Endocrine Society 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040054/
https://ncbi.nlm.nih.gov/pubmed/21209020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0782
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