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Modulation of sodium iodide symporter expression and function by LY294002, Akti-1/2 and Rapamycin in thyroid cells

The selective increase of Na(+)/I(−) symporter (NIS)-mediated active iodide uptake in thyroid cells allows the use of radioiodine I(131) for diagnosis and targeted treatment of thyroid cancers. However, NIS-mediated radioiodine accumulation is often reduced in thyroid cancers due to decreased NIS ex...

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Detalhes bibliográficos
Main Authors: Liu, Yu-Yu, Zhang, Xiaoli, Ringel, Matthew D, Jhiang, Sissy M
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736852/
https://ncbi.nlm.nih.gov/pubmed/22355179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-11-0288
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