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Modulation of thyroidal radioiodide uptake by oncological pipeline inhibitors and Apigenin

Targeted radioiodine therapy for thyroid cancer is based on selective stimulation of Na(+)/I(−) Symporter (NIS)-mediated radioactive iodide uptake (RAIU) in thyroid cells by thyrotropin. Patients with advanced thyroid cancer do not benefit from radioiodine therapy due to reduced or absent NIS expres...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lakshmanan, Aparna, Scarberry, Daniel, Green, Jill A., Zhang, Xiaoli, Selmi-Ruby, Samia, Jhiang, Sissy M.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741640/
https://ncbi.nlm.nih.gov/pubmed/26397139
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