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BRAF activates and physically interacts with PAK to regulate cell motility

Increased p21 activated kinase (PAK) signaling and expression has been identified in the invasive fronts of aggressive papillary thyroid cancers (PTCs), including those with RET/PTC, BRAF V600E, and mutant RAS expression. Functionally, thyroid cancer cell motility in vitro is dependent on Group 1 PA...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Endocr Relat Cancer
Egile Nagusiak: McCarty, Samantha K., Saji, Motoyasu, Zhang, Xiaoli, Knippler, Christina M., Kirschner, Lawrence S., Fernandez, Soledad, Ringel, Matthew D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487662/
https://ncbi.nlm.nih.gov/pubmed/25228413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-14-0424
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