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MAPK- and AKT-activated thyroid cancers are sensitive to group I PAK inhibition

The number of individuals who succumb to thyroid cancer has been increasing and those who are refractory to standard care have limited therapeutic options, highlighting the importance of developing new treatments for patients with aggressive forms of the disease. Mutational activation of MAPK signal...

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Detalhes bibliográficos
Publicado no:Endocr Relat Cancer
Main Authors: Knippler, Christina M., Saji, Motoyasu, Rajan, Neel, Porter, Kyle, La Perle, Krista M. D., Ringel, Matthew D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062234/
https://ncbi.nlm.nih.gov/pubmed/31146260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-19-0188
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