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Akt isoform-specific effects on thyroid cancer development and progression in a murine thyroid cancer model

The Akt family is comprised of three unique homologous proteins with isoform-specific effects, but isoform-specific in vivo data are limited in follicular thyroid cancer (FTC), a PI3 kinase-driven tumor. Prior studies demonstrated that PI3K/Akt signaling is important in thyroid hormone receptor β(PV...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Saji, Motoyasu, Kim, Caroline S., Wang, Chaojie, Zhang, Xiaoli, Khanal, Tilak, Coombes, Kevin, La Perle, Krista, Cheng, Sheue-Yann, Tsichlis, Philip N., Ringel, Matthew D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7591514/
https://ncbi.nlm.nih.gov/pubmed/33110146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75529-0
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