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Akt deficiency delays tumor progression, vascular invasion, and distant metastases in a murine model of thyroid cancer
Akt activation is common in progressive thyroid cancer. In breast cancer, Akt1 induced primary cancer growth, but is reported to inhibit metastasis in vivo in several model systems. In contrast, clinical and in vitro studies suggest a metastasis-promoting role for Akt1 in thyroid cancer. The goal of...
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| Hoofdauteurs: | , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2011
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3151477/ https://ncbi.nlm.nih.gov/pubmed/21532616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.136 |
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