Repeated Morphine Prolongs Postoperative Pain in Male Rats

BACKGROUND: Opioids are effective postoperative analgesics. Disturbingly, we have previously reported that opioids such as morphine can worsen inflammatory pain and peripheral and central neuropathic pain. These deleterious effects are mediated by immune mediators that promote neuronal hyperexcitabi...

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Detaylı Bibliyografya
Yayımlandı:Anesth Analg
Asıl Yazarlar: Grace, Peter M., Galer, Erika L., Strand, Keith A., Corrigan, Kaci, Berkelhammer, Debra, Maier, Steven F., Watkins, Linda R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054903/
https://ncbi.nlm.nih.gov/pubmed/29596097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0000000000003345
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