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Prior exposure to repeated morphine potentiates mechanical allodynia induced by peripheral inflammation and neuropathy

Opioids, such as morphine, induce potent analgesia and are the gold standard for the treatment of acute pain. However, opioids also activate glia, inducing pro-inflammatory cytokine and chemokine production, which counter-regulates the analgesic properties of classical opioid receptor activation. It...

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Detaylı Bibliyografya
Asıl Yazarlar: Loram, Lisa C., Grace, Peter M., Strand, Keith A., Taylor, Frederick R., Ellis, Amanda, Berkelhammer, Debra, Bowlin, Melissa, Skarda, Bryce, Maier, Steven F., Watkins, Linda R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491069/
https://ncbi.nlm.nih.gov/pubmed/22902523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2012.08.003
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