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DREADDed microglia in pain: implications for spinal inflammatory signaling in male rats
The absence of selective pharmacological tools is a major barrier to the in vivo study of microglia. To address this issue, we developed a G(q)- and G(i)-coupled Designer Receptor Exclusively Activated by a Designer Drug (DREADD) to enable selective stimulation or inhibition of microglia, respective...
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| Publicado no: | Exp Neurol |
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| Principais autores: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5916033/ https://ncbi.nlm.nih.gov/pubmed/29530713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2018.03.005 |
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