PKCβ and reactive oxygen species mediate enhanced pulmonary vasoconstrictor reactivity following chronic hypoxia in neonatal rats

Reactive oxygen species (ROS), mitochondrial dysfunction, and excessive vasoconstriction are important contributors to chronic hypoxia (CH)-induced neonatal pulmonary hypertension. On the basis of evidence that PKCβ and mitochondrial oxidative stress are involved in several cardiovascular and metabo...

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Detaylı Bibliyografya
Yayımlandı:Am J Physiol Heart Circ Physiol
Asıl Yazarlar: Sheak, Joshua R., Yan, Simin, Weise-Cross, Laura, Ahmadian, Rosstin, Walker, Benjimen R., Jernigan, Nikki L., Resta, Thomas C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052628/
https://ncbi.nlm.nih.gov/pubmed/31922892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00629.2019
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