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Enhanced NO-dependent pulmonary vasodilation limits increased vasoconstrictor sensitivity in neonatal chronic hypoxia

Augmented vasoconstrictor reactivity is thought to play an important role in the development of chronic hypoxia (CH)-induced neonatal pulmonary hypertension. However, whether this response to CH results from pulmonary endothelial dysfunction and reduced nitric oxide (NO)-mediated vasodilation is not...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Sheak, Joshua R., Weise-Cross, Laura, deKay, Ray J., Walker, Benjimen R., Jernigan, Nikki L., Resta, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668609/
https://ncbi.nlm.nih.gov/pubmed/28733445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00123.2017
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