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PKCβ and reactive oxygen species mediate enhanced pulmonary vasoconstrictor reactivity following chronic hypoxia in neonatal rats

Reactive oxygen species (ROS), mitochondrial dysfunction, and excessive vasoconstriction are important contributors to chronic hypoxia (CH)-induced neonatal pulmonary hypertension. On the basis of evidence that PKCβ and mitochondrial oxidative stress are involved in several cardiovascular and metabo...

詳細記述

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書誌詳細
出版年:Am J Physiol Heart Circ Physiol
主要な著者: Sheak, Joshua R., Yan, Simin, Weise-Cross, Laura, Ahmadian, Rosstin, Walker, Benjimen R., Jernigan, Nikki L., Resta, Thomas C.
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052628/
https://ncbi.nlm.nih.gov/pubmed/31922892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00629.2019
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