Intermittent Hypoxia Augments Pulmonary Vasoconstrictor Reactivity through PKCβ/Mitochondrial Oxidant Signaling

Pulmonary vasoconstriction resulting from intermittent hypoxia (IH) contributes to pulmonary hypertension (pHTN) in patients with sleep apnea (SA), although the mechanisms involved remain poorly understood. Based on prior studies in patients with SA and animal models of SA, the objective of this stu...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Snow, Jessica B., Norton, Charles E., Sands, Michelle A., Weise-Cross, Laura, Yan, Simin, Herbert, Lindsay M., Sheak, Joshua R., Gonzalez Bosc, Laura V., Walker, Benjimen R., Kanagy, Nancy L., Jernigan, Nikki L., Resta, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7258822/
https://ncbi.nlm.nih.gov/pubmed/32048876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2019-0351OC
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