Augmented Pulmonary Vasoconstrictor Reactivity after Chronic Hypoxia Requires Src Kinase and Epidermal Growth Factor Receptor Signaling

Chronic hypoxia augments pressure- and agonist-induced pulmonary vasoconstriction through myofilament calcium sensitization. NADPH oxidases contribute to the development of pulmonary hypertension, and both epidermal growth factor receptor and Src kinases can regulate NADPH oxidase. We tested the hyp...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Am J Respir Cell Mol Biol
Auteurs principaux: Norton, Charles E., Sheak, Joshua R., Yan, Simin, Weise-Cross, Laura, Jernigan, Nikki L., Walker, Benjimen R., Resta, Thomas C.
Format: Artigo
Langue:Inglês
Publié: American Thoracic Society 2020
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938133/
https://ncbi.nlm.nih.gov/pubmed/31264901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2018-0106OC
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires