載入...
CRISPR-Cas12a Possesses Unconventional DNase Activity that Can Be Inactivated by Synthetic Oligonucleotides
CRISPR-Cas12a (CRISPR-Cpf1) was reported to have multiple types of cleavage activities. Without the assistance of CRISPR RNA (crRNA), we investigated DNase activity and substrate specificity of Cas12a orthologs in the presence of diverse divalent metal ions. Cas12a from different species are capable...
Na minha lista:
| 發表在: | Mol Ther Nucleic Acids |
|---|---|
| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society of Gene & Cell Therapy
2020
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7015830/ https://ncbi.nlm.nih.gov/pubmed/32045875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.12.038 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|