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Leveraging mRNA Sequences and Nanoparticles to Deliver SARS-CoV-2 Antigens In Vivo

SARS-CoV-2 has become a pandemic worldwide; therefore, an effective vaccine is urgently needed. Recently, messenger RNAs (mRNAs) have emerged as a promising platform for vaccination. In this work, the untranslated regions (UTRs) of mRNAs are systematically engineered in order to enhance protein prod...

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Podrobná bibliografie
Vydáno v:Adv Mater
Hlavní autoři: Zeng, Chunxi, Hou, Xucheng, Yan, Jingyue, Zhang, Chengxiang, Li, Wenqing, Zhao, Weiyu, Du, Shi, Dong, Yizhou
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8191860/
https://ncbi.nlm.nih.gov/pubmed/32875709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adma.202004452
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