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Leveraging mRNAs sequences to express SARS-CoV-2 antigens in vivo

SARS-CoV-2 has rapidly become a pandemic worldwide; therefore, an effective vaccine is urgently needed. Recently, messenger RNAs (mRNAs) have emerged as a promising platform for vaccination. Here, we systematically investigated the untranslated regions (UTRs) of mRNAs in order to enhance protein pro...

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Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Zeng, Chunxi, Hou, Xucheng, Yan, Jingyue, Zhang, Chengxiang, Li, Wenqing, Zhao, Weiyu, Du, Shi, Dong, Yizhou
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217301/
https://ncbi.nlm.nih.gov/pubmed/32511313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.04.01.019877
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