A carregar...
Engineering CRISPR-Cpf1 crRNAs and mRNAs to maximize genome editing efficiency
Cpf1, a type-V CRISPR-Cas effector endonuclease, exhibits gene-editing activity in human cells through a single RNA-guided approach. Here, we report the design and assessment of an array of 42 types of engineered Acidaminococcus sp. Cpf1 (AsCpf1) CRISPR RNAs (crRNAs) and 5 types of AsCpf1 mRNAs, and...
Na minha lista:
| Publicado no: | Nat Biomed Eng |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5562407/ https://ncbi.nlm.nih.gov/pubmed/28840077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41551-017-0066 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|