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Targeted delivery of atorvastatin via asialoglycoprotein receptor (ASGPR)
Targeted drug delivery platforms can increase the concentration of drugs in specific cell populations, reduce adverse effects, and hence improve the therapeutic effect of drugs. Herein, we designed two conjugates by installing the targeting ligand GalNAc (N-acetylgalactosamine) onto atorvastatin (AT...
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| Publicado en: | Bioorg Med Chem |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6535107/ https://ncbi.nlm.nih.gov/pubmed/31005367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2019.04.019 |
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