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Targeted delivery of atorvastatin via asialoglycoprotein receptor (ASGPR)
Targeted drug delivery platforms can increase the concentration of drugs in specific cell populations, reduce adverse effects, and hence improve the therapeutic effect of drugs. Herein, we designed two conjugates by installing the targeting ligand GalNAc (N-acetylgalactosamine) onto atorvastatin (AT...
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| Publicado no: | Bioorg Med Chem |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6535107/ https://ncbi.nlm.nih.gov/pubmed/31005367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2019.04.019 |
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