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Consequences of CRISPR-Cas9-Mediated CFTR Knockout in Human Macrophages
Macrophage dysfunction is fundamentally related to altered immunity in cystic fibrosis (CF). How genetic deficits in the cystic fibrosis transmembrane conductance regulator (CFTR) lead to these defects remains unknown. Rapid advances in genomic editing such as the clustered regularly interspaced sho...
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| Publicado no: | Front Immunol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7461958/ https://ncbi.nlm.nih.gov/pubmed/32973772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01871 |
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