Multi-omic Characterization of the Mode of Action of a Potent New Antimalarial Compound, JPC-3210, Against Plasmodium falciparum

The increasing incidence of antimalarial drug resistance to the first-line artemisinin combination therapies underpins an urgent need for new antimalarial drugs, ideally with a novel mode of action. The recently developed 2-aminomethylphenol, JPC-3210, (MMV 892646) is an erythrocytic schizonticide w...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Birrell, Geoffrey W., Challis, Matthew P., De Paoli, Amanda, Anderson, Dovile, Devine, Shane M., Heffernan, Gavin D., Jacobus, David P., Edstein, Michael D., Siddiqui, Ghizal, Creek, Darren J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000111/
https://ncbi.nlm.nih.gov/pubmed/31836637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA119.001797
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