Multi-omic Characterization of the Mode of Action of a Potent New Antimalarial Compound, JPC-3210, Against Plasmodium falciparum

The increasing incidence of antimalarial drug resistance to the first-line artemisinin combination therapies underpins an urgent need for new antimalarial drugs, ideally with a novel mode of action. The recently developed 2-aminomethylphenol, JPC-3210, (MMV 892646) is an erythrocytic schizonticide w...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell Proteomics
Prif Awduron: Birrell, Geoffrey W., Challis, Matthew P., De Paoli, Amanda, Anderson, Dovile, Devine, Shane M., Heffernan, Gavin D., Jacobus, David P., Edstein, Michael D., Siddiqui, Ghizal, Creek, Darren J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Biochemistry and Molecular Biology 2020
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000111/
https://ncbi.nlm.nih.gov/pubmed/31836637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA119.001797
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