JPC-2997, a New Aminomethylphenol with High In Vitro and In Vivo Antimalarial Activities against Blood Stages of Plasmodium

4-(tert-Butyl)-2-((tert-butylamino)methyl)-6-(6-(trifluoromethyl)pyridin-3-yl)-phenol (JPC-2997) is a new aminomethylphenol compound that is highly active in vitro against the chloroquine-sensitive D6, the chloroquine-resistant W2, and the multidrug-resistant TM90-C2B Plasmodium falciparum lines, wi...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Birrell, Geoffrey W., Chavchich, Marina, Ager, Arba L., Shieh, Hong-Ming, Heffernan, Gavin D., Zhao, Wenyi, Krasucki, Peter E., Saionz, Kurt W., Terpinski, Jacek, Schiehser, Guy A., Jacobus, Laura R., Shanks, G. Dennis, Jacobus, David P., Edstein, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Susceptibility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291346/
https://ncbi.nlm.nih.gov/pubmed/25331702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03762-14
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