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Lead Selection of a New Aminomethylphenol, JPC-3210, for Malaria Treatment and Prevention
Structure-activity relationship studies of trifluoromethyl-substituted pyridine and pyrimidine analogues of 2-aminomethylphenols (JPC-2997, JPC-3186, and JPC-3210) were conducted for preclinical development for malaria treatment and/or prevention. Of these compounds, JPC-3210 [4-(tert-butyl)-2-((ter...
Gespeichert in:
| Veröffentlicht in: | Antimicrob Agents Chemother |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4862471/ https://ncbi.nlm.nih.gov/pubmed/26856849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03066-15 |
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